For males only, sorry ladies, we are still searching. Finally, a natural formula for aiding sexual response in men THAT ACTUALLY WORKS and IS SAFE. An all natural herbal formula used for several thousand years in the orient. This formula impacts the Thalamus and Pituitary Gland, which controls sexual organ functions. Unlike other products which may cause a heart attack or a stroke, Rise & Shine is not a vasodilator. This totally natural formula has been used for centuries in the male dominant societies of Asia. The effect from this product may last off and on from 2 to 24 hours. Dr. Maclean says this is the best, all natural product, of its kind.